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S4 (Andarine) or acetamide oxolutamide in Barbarian Research is a SARM (selective androgen receptor modulator). Developed as a drug to reduce muscle wasting-SARMs are a multi-purpose compound that can help increase strength, muscle and reduce fat. Andarine's special function is to help oxidize fat and prevent the body from catabolism, and low-calorie diet is its specialty. It will provide a hard, dry, lean look and increase blood vessels. It provides significant strength and endurance, even at low calories and at high doses, it can even increase your body's hard muscles. MK677 (Ibutamoren) in Barbarian Research is an effective oral growth hormone secretagogue that mimics the somatotropin effect of the endogenous hormone ghrelin. It has been shown that it increases the release of several hormones in the plasma and keeps it rising, including growth hormone and IGF-1, but does not affect cortisol levels.